ASIC3 Polyclonal Antibody (E-AB-19330)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human colorectal cancer |
| Dilution | IHC 1:30-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ASIC3 |
| Abbre | ASIC3 |
| Synonyms | ACCN 3, ACCN3, ASIC 3, ASIC3, Accn3, Acid sensing ion channel 3, Acid-sensing ion channel 3, Amiloride sensitive cation channel 3, Amiloride sensitive cation channel 3 testis, Amiloride-sensitive cation channel 3, DRASIC, Modulatory sub, hASIC 3, hASIC3, hTNaC 1, hTNaC1 |
| Swissprot | |
| Cellular Localization | Cell membrane. Cytoplasm. Cell surface expression may be stabilized by interaction with LIN7B and cytoplasmic retention by interaction with DLG4. In part cytoplasmic in cochlea cells. |
| Concentration | 1.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily.The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing.The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes.In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium.Alternatively spliced transcript variants have been described. |
Other Clones
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Other Formats
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Unconjugated
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