ARHGEF2 Polyclonal Antibody (E-AB-14606)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human breast cancer, Human lung cancer |
| Dilution | IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ARHGEF2 |
| Abbre | ARHGEF2 |
| Synonyms | AA408978, ARHG2, ARHGEF 2, ARHGEF-2, ARHGEF2, GEF, GEF H1, GEF-H1, GEFH1, Guanine nucleotide exchange factor H1, KIAA0651, LFP40, Lbcl1, Lfc, MGC95068, Microtubule-regulated Rho-GEF, P40, Proliferating cell nucleolar antigen p40, Protein GEF-H1, Rho guanine , mKIAA0651 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Cell junction>tight junction. Golgi apparatus. Cytoplasm>cytoskeleton>spindle. Cell projection>ruffle membrane. Localizes to the tips of cortical microtubules of the mitotic spindle during cell division, and is further released upon microtubule depolymerization. Recruited into membrane ruffles induced by S.flexneri at tight junctions of polarized epithelial cells. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Other Clones
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Other Formats
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Unconjugated
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