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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human tonsil
Dilution IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
ClonalityPolyclonal
ImmunogenSynthetic peptide of human AQP2
AbbreAQP2
SynonymsADH water channel,  AQP 2,  AQP CD,  AQP-2,  AQP-CD,  AQP2,  AQPCD,  Aquaporin 2 collecting duct,  Aquaporin CD,  Aquaporin-2,  Aquaporin-CD,  Aquaporin2,  Aquaporine 2,  Collecting duct water channel protein,  MGC34501,  Water channel aquaporin 2,  Water channel protein for renal
Swissprot
Cellular LocalizationApical cell membrane. Basolateral cell membrane. Cytoplasmic vesicle membrane. Golgi apparatus, trans-Golgi network membrane. Shuttles from vesicles to the apical membrane. Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane. PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated.
Concentration0.7 mg/mL
BufferPhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification MethodAffinity purification
Research AreasCancer,  Metabolism,  Signal Transduction
ConjugationUnconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
ShippingThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
backgroundThe basic job of aquaporin 2 is to reabsorb water from the urine while its being removed from the blood by the kidney. Aquaporin 2 is in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes, but when it is needed vasopressin binds to the cell surface vasopressin receptor, activating a signaling pathway that causes the aquaporin 2 containing vesicles to fuse with the plasma membrane so the aquaporin 2 can be used by the cell.
Other Clones

1 Results

    Other Formats

    1 Results

    Unconjugated