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For research use only.
Verified Samples | Verified Samples in IHC: Human liver cancer, Human tonsil |
Dilution | IHC 1:100-1:300 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human AQP2 |
Abbre | AQP2 |
Synonyms | ADH water channel, AQP 2, AQP CD, AQP-2, AQP-CD, AQP2, AQPCD, Aquaporin 2 collecting duct, Aquaporin CD, Aquaporin-2, Aquaporin-CD, Aquaporin2, Aquaporine 2, Collecting duct water channel protein, MGC34501, Water channel aquaporin 2, Water channel protein for renal |
Swissprot | |
Cellular Localization | Apical cell membrane. Basolateral cell membrane. Cytoplasmic vesicle membrane. Golgi apparatus, trans-Golgi network membrane. Shuttles from vesicles to the apical membrane. Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane. PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated. |
Concentration | 0.7 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Metabolism, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The basic job of aquaporin 2 is to reabsorb water from the urine while its being removed from the blood by the kidney. Aquaporin 2 is in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes, but when it is needed vasopressin binds to the cell surface vasopressin receptor, activating a signaling pathway that causes the aquaporin 2 containing vesicles to fuse with the plasma membrane so the aquaporin 2 can be used by the cell. |
Other Clones
1 Results
Other Formats
1 Results
Unconjugated