APC5 Polyclonal Antibody (E-AB-10810)

For research use only.
Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human liver cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human ANAPC5 |
Abbre | APC5 |
Synonyms | 2510006G12Rik, AA408751, AA536819, AA986414, ANAPC 5, ANAPC5, APC5, Anaphase promoting complex subunit 5, Anaphase-promoting complex subunit 5, Apc 5, Cyclosome subunit 5, PDL 108, PDL108, Periodontal ligament fibroblast protein, RMC1 |
Swissprot | |
Cellular Localization | Cytosol, Nucleus, anaphase-promoting complex, nucleoplasm, nucleus. |
Concentration | 0.3 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cell Biology |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination.The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators.It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation.Multiple transcript variants encoding different isoforms have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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