APC Anti-Mouse CD200/OX2 Antibody[OX-90] (E-AB-F1234UE)
For research use only.
| Alternate Names | MRC, OX-2, OX-2 membrane glycoprotein |
| Clone No | |
| Leadtime | Order now, ship in 3 days |
| Background | CD200 (OX-2 antigen) is a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, B cells, and brain tissue (neurons); but not on NK cells, granulocytes, monocytes, or macrophages. CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues. CD200 is the ligand for CD200 receptor (CD200R). The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or downregulation of myeloid cell activity. Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation. |
| Abbre | CD200 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype | Rat IgG2a, κ |
| Isotype Control | E-AB-F09833E |
| Applications |
FCM
|
| Research Areas | Cell Biology;Costimulatory Molecules;Immunology;Neuroscience;Neuroscience Cell Markers |
| Cellular Localization |
Membrane
|
| Form | Liquid |
| Concentration |
0.2 mg/mL
|
| Conjugation | APC |
| Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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Other Formats
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APC
Elab Fluor®700
FITC
None (AF/LE)
PE
PE/Cyanine 7
Unconjugated
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