APC Anti-Human IL-21 Antibody[3A3-N2] (E-AB-F1202E)

For research use only.
Alternate Names | IL-21, Interleukin-21, Za11 |
Clone No | |
Leadtime | Order now, ship in 3 days |
Background | Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases. |
Abbre | IL-21 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG1, κ |
Isotype Control | E-AB-F09792E |
Applications |
ICFCM
|
Research Areas | Immunology;Innate Immunity |
Cellular Localization |
Secreted
|
Form | Liquid |
Concentration |
5 μL/Test
|
Conjugation | APC |
Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12 months |
Shipping | Ice bag |
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