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APC Anti-Human CD274/PD-L1 Antibody[29E.2A3] (E-AB-F1133E)

AllSizePriceQty
100Tests $ 204.00
20Tests $ 90.00
100Tests×2 $ 312.00
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For research use only.

Alternate NamesB7H1PD-L1PDCD1L1PDCD1LG1PDL1,  B7 homolog 1,  B7-H,  B7-H1,  Programmed cell death ligand 1
Clone No
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BackgroundCD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
AbbrePD-L1
Swissprot
HostMouse
ReactivityHuman
ClonalityMonoclonal
Isotype Mouse IgG2b, κ
Isotype Control E-AB-F09812E
Applications
FCM
Research AreasCancer Biomarkers;Costimulatory Molecules;Immunology
Cellular Localization
Membrane
FormLiquid
Concentration
5 μL/Test
ConjugationAPC
Conjugation InformationAPC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage BufferPhosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
StorageThis product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date12 months
ShippingIce bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Other Clones

1 Results

    Other Formats

    1 Results

    APC

    Biotin

    Elab Fluor®700

    FITC

    None (AF/LE)

    PE

    PE/Cyanine 5

    PE/Cyanine 7

    PerCP/Cyanine 5.5

    Unconjugated