APC Anti-Human CD273/PD-L2 Antibody[24F.10C12] (E-AB-F1175E)

For research use only.
Alternate Names | CD273PDCD1L2PDL2, B7DC |
Clone No | |
Leadtime | Order now, ship in 3 days |
Background | CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions. |
Abbre | CD273 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG2a, κ |
Isotype Control | E-AB-F09802E |
Applications |
FCM
|
Research Areas | Costimulatory Molecules;Immunology |
Cellular Localization |
Membrane
|
Form | Liquid |
Concentration |
5 μL/Test
|
Conjugation | APC |
Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12 months |
Shipping | Ice bag |
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APC
Elab Fluor®700
None (AF/LE)
PE
Unconjugated
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