AP2A1 Polyclonal Antibody (E-AB-17662)
For research use only.
| Verified Samples |
Verified Samples in WB: A431, 231, NIH/3T3 Verified Samples in IHC: Human liver cancer |
| Dilution | WB 1:500-2000, IHC 1:25-100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human AP2A1 |
| Abbre | AP2A1 |
| Synonyms | 100 kDa coated vesicle protein A, Ad, Adapter-related protein complex 2 alpha-1 subunit, Adaptin alpha, Adaptin alpha A, Adaptor protein complex AP 2 alpha 1 subunit, adapter-related protein complex 2 subunit alpha-1, adaptor protein complex AP 2 subunit alpha 1 |
| Swissprot | |
| Calculated MW | 108 kDa |
| Cellular Localization | Cell membrane. Membrane>coated pit. AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. |
Other Clones
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Other Formats
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Unconjugated
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