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For research use only.

Verified Samples Verified Samples in IF: MCF-7
Dilution IF 1:100-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IF
Clonality Polyclonal
Immunogen Recombinant Human Amphiregulin protein expressed by E.coli
Abbre Amphiregulin
Synonyms KAF,  AREG,  AR,  AREGB,  CRDGF,  SDGF,  amphiregulin,  Colorectum Cell-Derived Growth Factor
Swissprot
Cellular Localization Cell membrane
Concentration 1 mg/mL
Buffer PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Purification Method Antigen Affinity Purification
Research Areas Signal Transduction,  Cancer
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
background The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.
Other Clones

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Unconjugated

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