AF/LE Purified Anti-Mouse IL-17A Antibody[17F3] (E-AB-F12720)
For research use only.
| Alternate Names | IL-17CTLA, Cytotoxic T-lymphocyte-associated antigen, IL-17Acytotoxic T-lymphocyte-associated protein, CTLA8cytotoxic T-lymphocyte-associated serine esterase, CTLA 8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Ctla9, IL-17A, IL-17Acytotoxic T-lymphocyte-associated protein 8, IL-17CTLA-8, Interleukin-17A, IL-17, CTLA-8, Il17a, Cytotoxic T-lymphocyte-associated antigen 8, Ctla8, Il17, CTLA8, CTLA-8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL-17, IL17A, IL-17A, IL-17Acytotoxic T-lymphocyte-associated protein 8, IL-17CTLA-8 |
| Clone No | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Mouse IL-17A gene |
| Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
| Background | The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A in vivo. |
| Immunogen | Recombinant Mouse IL-17A protein |
| Abbre | IL-17A |
| Swissprot | |
| Host | Mouse |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Applications |
ICFCM
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®647
Elab Fluor®700
Elab Fluor®Violet 450
FITC
None (AF/LE)
None (AF/LE)
PE
PE/Cyanine 7
Unconjugated
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