AF/LE Purified Anti-Mouse CD120b/TNFR2 Antibody[TR75-54.7] (E-AB-F10350)
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For research use only.
Alternate Names | CD120b, TNF-R2, TNF-RII, TNFR-II, Tnfrsf1b, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor superfamily member 1B, p75, p80 TNF-alpha receptor |
Clone No | |
Leadtime | Order now, ship in 3 days |
Background | CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state. |
Abbre | CD120b/TNFR2 |
Swissprot | |
Host | Armenian Hamster |
Reactivity | Mouse |
Clonality | Monoclonal |
Isotype | Armenian Hamster IgG |
Applications | FCM;Block |
Research Areas | Immunology;Innate Immunity |
Concentration | ≥ 1 mg/mL |
Conjugation | None (AF/LE) |
Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
Expiration Date | 12 months |
Shipping | Ice bag |
Other Clones
1 Results
Other Formats
1 Results
None (AF/LE)
Unconjugated
