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For research use only.
| Alternate Names | LAB, CTLA-4 counter-receptor B, T-lymphocyte activation antigen CD, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7, CD80, CD28LGB7-1 antigen, T-lymphocyte activation antigen CD80, Activation B7-1 antigen, CTLA-4 counter-receptor B7.1, B7-1, BB1, B lymphocyte activation antigen B7, B7-1 antigen, B7-1 antigen), CD28 antigen ligand 1, CD80 antigen, CD80 antigen (CD28 antigen ligand 1, CD80 molecule, Costimulatory factor CD80, costimulatory molecule variant IgV-CD80 |
| Clone No | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Raji |
| Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
| Background | B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20‑100 fold higher affinity than CD28 and is involved in the down‑regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. |
| Immunogen | Recombinant Human CD80 protein |
| Abbre | CD80 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Applications | FCM |
| Research Areas | Immunology;Stem Cells |
| Concentration | ≥ 1 mg/mL |
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
1 Results
Other Formats
1 Results
APC
Biotin
Elab Fluor®700
Elab Fluor®Red 780
Elab Fluor®Violet 450
Elab Fluor®Violet 610
FITC
None (AF/LE)
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP/Cyanine 5.5
Unconjugated
