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AF/LE Purified Anti-Human CD279/PD-1 Antibody[J110] (E-AB-F12130)

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AllSizePriceQty
100μg $ 50.00
25μg $ 20.00
100mg $ 4100.00
50mg $ 2850.00
25mg $ 1900.00
5mg $ 570.00
1mg $ 156.00
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For research use only.

Alternate NamesPD1,  PDCD1,  Protein PD-1,  hPD-1
Clone No
Leadtime Order now, ship in 3 days
BackgroundProgrammed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
AbbreCD279/PD-1
Swissprot
HostMouse
ReactivityHuman
ClonalityMonoclonal
Isotype Mouse IgG1, κ
Applications
FCM
Research AreasCancer Biomarkers;Immunology;Inhibitory Molecules
Concentration
≥ 1 mg/mL
ConjugationNone (AF/LE)
Storage BufferSterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
StorageStore at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Expiration Date12 months
ShippingIce bag
Cat.No. Product Name Sizes
E-AB-F1213A Purified Anti-Human CD279/PD-1 Antibody[J110] 100μg , 25μg , 100mg , 50mg , 25mg , 5mg , 1mg
Other Clones

1 Results

    Other Formats

    1 Results

    None (AF/LE)

    Unconjugated

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