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For research use only.
| Verified Samples | Verified Samples in IHC: Human liver cancer, Human brain |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ACLY |
| Abbre | ACLY |
| Synonyms | ACL, ACLY, ATP citrate (pro-S) lyase, ATP citrate lyase, ATP citrate synthase, ATP-citrate (pro-S-)-lyase, ATP-citrate synthase, ATPCL, ATPcitrate synthase, Acly, CLATP, Citrate cleavage enzyme, OTTHUMP00000164773 |
| Swissprot | |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. |
Other Clones
1 Results
Other Formats
1 Results
Unconjugated
