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For research use only.

Verified Samples Verified Samples in IF: NIH/3T3
Dilution IF 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Mouse,  Rat
Applications IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human ABCA1
Abbre ABCA1
Synonyms ABC-1,  ABC1,  ABCA1,  CERP,  HDLDT1,  TGD
Swissprot
Calculated MW 254 kDa
Cellular Localization Membrane, Multi-pass membrane protein.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Neuroscience,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
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Unconjugated

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