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For research use only.

Verified Samples Verified Samples in WB: Hela, Mouse kidney
Verified Samples in IHC: Human lung cancer, Human colon cancer
Dilution WB 1:500-1:2000,  IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human YWHAB
Abbre 14-3-3 beta/alpha
Synonyms 14 3 3 alpha,  14 3 3 protein beta/alpha,  14-3-3 protein beta/alpha,  1433B,  Brain protein 14 3 3 beta isoform,  GW128,  HS 1,  KCIP-1,  KCIP1,  N-terminally processed,  Protein 1054,  Protein kinase C inhibitor protein 1,  YWHAA,  YWHAB
Swissprot
Calculated MW 28 kDa
Cellular Localization Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Neuroscience,  Signal Transduction,  Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.
Other Clones

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Unconjugated

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