ZKSCAN3 Polyclonal Antibody (E-AB-18451)

For research use only.
Verified Samples |
Verified Samples in IHC: Human lung cancer, Human esophagus cancer |
Dilution | IHC 1:40-1:250 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Fusion protein of human ZKSCAN3 |
Abbre | ZKSCAN3 |
Synonyms | isoform CRA_a, SCAN-KRAB-zinc finger protein, Skz1, ZFP306, Zf47, Zfp-47, Zfp307, Zfp47, Zinc fi, Zinc finger and SCAN domain containing protein 13, Zinc finger and SCAN domain-containing protein 13, Zinc finger protein 306, dJ874C20.1, mszf35 |
Swissprot | |
Cellular Localization | Nucleus. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas. |
Other Clones
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Other Formats
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Unconjugated
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