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For research use only.
| Verified Samples | Verified Samples in WB: A375, Hela, Jurkat Verified Samples in IHC: Human skin |
| Dilution | WB 1:500-1:2000, IHC 1:50-200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human TYR |
| Abbre | TYR |
| Synonyms | ATN, CMM8, LB24 AB, LB24-AB, Monophenol monooxygenase, OCA1, OCA1A, OCAIA, Oculocutaneous albinism IA, SHEP3, SK29 AB, SK29-AB, TYR, TYRO, Tumor rejection antigen AB, Tyrosinase, tyrosinase (oculocutaneous albinism IA) |
| Swissprot | |
| Calculated MW | 60 kDa |
| Cellular Localization | Melanosome membrane. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. |
Other Clones
1 Results
Other Formats
1 Results
Unconjugated
