TNF beta Polyclonal Antibody (E-AB-14410)

For research use only.
Verified Samples |
Verified Samples in IHC: Human colon cancer, Human lung cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human LTA |
Abbre | LTA |
Synonyms | DIF, LT, LT alpha, LT-alpha, LTalpha, Lta, Lymphotoxin alpha, Lymphotoxin alpha (TNF superfamily, Lymphotoxin-alpha, TNF, TNF B, TNF superfamily member 1, TNF-beta, TNFB, TNFSF1, TNFbeta, TNLG1E, Tumor necrosis factor beta, lymphocyte-derived, member 1), tumor necrosis |
Swissprot | |
Cellular Localization | Secreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated. |
Concentration | 0.5 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Immunology, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. |
Other Clones
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Other Formats
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Unconjugated
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