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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer, Human lung cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human LTA
Abbre LTA
Synonyms DIF,  LT,  LT alpha,  LT-alpha,  LTalpha,  Lta,  Lymphotoxin alpha,  Lymphotoxin alpha (TNF superfamily,  Lymphotoxin-alpha,  TNF,  TNF B,  TNF superfamily member 1,  TNF-beta,  TNFB,  TNFSF1,  TNFbeta,  TNLG1E,  Tumor necrosis factor beta,  lymphocyte-derived,  member 1),  tumor necrosis
Swissprot
Cellular Localization Secreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Immunology,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.
Other Clones

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Unconjugated

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