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For research use only.

Verified Samples Verified Samples in IHC: Rat ovary, Human breast cancer
Verified Samples in IF: HeLa
Dilution IHC 1:50-1:200,  IF 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC,  IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human Smad5 (NP_001001420.1).
Abbre Smad5
Synonyms DWFC,  JV5-1,  MADH5,  SMAD5
Swissprot
Cellular Localization Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling,  Developmental Biology,  Signal Transduction,  Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.
Other Clones

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Unconjugated

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