Smad5 Polyclonal Antibody (E-AB-66198)

For research use only.
Verified Samples |
Verified Samples in IHC: Rat ovary, Human breast cancer Verified Samples in IF: HeLa |
Dilution | IHC 1:50-1:200, IF 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC, IF |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human Smad5 (NP_001001420.1). |
Abbre | Smad5 |
Synonyms | DWFC, JV5-1, MADH5, SMAD5 |
Swissprot | |
Cellular Localization | Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Signal Transduction, Stem Cells |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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