Rb Polyclonal Antibody (E-AB-67411)

For research use only.
Verified Samples |
Verified Samples in IF: Y79 |
Dilution | IF 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IF |
Clonality | Polyclonal |
Immunogen | A synthetic peptide of human Rb (NP_000312.2). |
Abbre | Rb |
Synonyms | OSRC, PPP1R130, RB, RB1, Rb, p105-Rb, pRb, pp110 |
Swissprot | |
Cellular Localization | Nucleus. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
Other Clones
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Other Formats
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Unconjugated
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