PLK1 Polyclonal Antibody (E-AB-60722)

Citations ({{ citationsPage.numTotal }}) Manual MSDS

All	Size	Price	Qty
	200μL	$ 530.00
	120μL	$ 320.00
	60μL	$ 200.00

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Verified Samples	Verified Samples in IF: C6, NIH/3T3, U-2OS
Dilution	IF 1:50-1:200
Isotype	IgG
Host	Rabbit
Reactivity	Human, Mouse, Rat
Applications	IF
Clonality	Polyclonal
Immunogen	Recombinant fusion protein of human PLK1 (NP_005021.2).
Abbre	PLK1
Synonyms	PLK, PLK1, STPK13
Swissprot	P53350
Cellular Localization	Nucleus. Chromosome>centromere>kinetochore. Cytoplasm>cytoskeleton>centrosome. During early stages of mitosis, the phosphorylated form is detected on centrosomes and kinetochores. Localizes to the outer kinetochore. Presence of SGOL1 and interaction with the phosphorylated form of BUB1 is required for the kinetochore localization.
Concentration	1 mg/mL
Buffer	Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method	Affinity purification
Research Areas	Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background	The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.

Cat.No.	Product Name	Sizes
E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1010	Goat Anti-Rabbit IgG(H+L)(Cyanine3 conjugated)	500μL , 120μL , 60μL
E-AB-1014	Goat Anti-Rabbit IgG(H+L)(FITC conjugated)	500μL , 120μL , 60μL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1060	Goat Anti-Rabbit IgG(H+L)(Elab Fluor^® 594 conjugated)	500μL , 120μL , 60μL
E-AB-1075	Goat Anti-Rabbit IgG(H+L)(Elab Fluor^® 647 conjugated)	500μL , 120μL , 60μL
E-AB-1099	Elab Fluor^® Violet 450-Goat Anti-Rabbit IgG(H+L)	500μL , 120μL , 1mL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500μL , 120μL , 1mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50mL , 18mL , 6mL , 3mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50Assays

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Unconjugated