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For research use only.

Verified Samples Verified Samples in IF: U2OS, U2OS
Dilution IF 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human PIAS1 (NP_057250.1).
Abbre PIAS1
Synonyms DDXBP1,  GBP,  GU/RH-II,  PIAS1,  ZMIZ3
Swissprot
Cellular Localization Nucleus speckle. Interaction with CSRP2 may induce a partial redistribution along the cytoskeleton.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants.
Other Clones

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Unconjugated

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