Pancreatic polypeptide/PPY Polyclonal Antibody (AN000330P)
For research use only.
| Verified Samples | Verified Samples in ELISA: Recombinant Human Pancreatic polypeptide/PPY protein, Human serum, Human plasma |
| Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
| Isotype | Rat IgG |
| Host | Rat |
| Reactivity | Human |
| Applications | ELISA Capture/Detector |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human Pancreatic polypeptide/PPY protein expressed by E.coli |
| Abbre | Pancreatic polypeptide/PPY |
| Synonyms | Pancreatic poLypeptide prohormone, PH, Pancreatic poLypeptide Y, Pancreatic poLypeptide, Pancreatic icosapeptide, PPY, PNP |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | Pancreatic polypeptide (PP),36-amino acid peptide,may function as an important feedback inhibitor of pancreatic secretion after a meal. It arises from both islet and acinar cells of the pancreas. Release of PP by a meal,primarily protein,occurs in a biphasic manner. PP is a negative regulator of energy homeostasis that suppresses food intake and lowers body weight. Similar to other gastrointestinal-derived peptides,PP also modulates gastrointestinal motility and may be involved in the regulation of anxiety. PP,a robust anorexigenic hormone,effectively modulates food intake and energy homeostasis,thus potentially aiding anti-obesity therapeutics. PP is produced in pancreatic islets of Langerhans and released into the circulation after ingestion of a meal. Peripherally administered PP suppresses food intake and gastric emptying. On the other hand,central administration of PP elicits food intake and gastric emptying. |
Other Clones
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Other Formats
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Unconjugated
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