MYC Polyclonal Antibody (E-AB-63525)
For research use only.
| Verified Samples |
Verified Samples in IHC: Mouse liver, Rat heart |
| Dilution | IHC 1:50-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | A synthetic peptide of human MYC (NP_002458.2). |
| Abbre | MYC |
| Synonyms | MRTL, MYC, MYCC, bHLHe39, c-Myc |
| Swissprot | |
| Cellular Localization | Nucleus>nucleoplasm. Nucleus>nucleolus. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. |
Other Clones
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Other Formats
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Unconjugated
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