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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer
Dilution IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
ClonalityPolyclonal
ImmunogenSynthetic peptide of human ADRBK1
AbbreADRBK1
SynonymsADRBK1,  ARBK1,  Adrenergic beta receptor kinase 1,  BARK,  BARK1,  Beta ARK 1,  Beta ARK1,  Beta adrenergic receptor kinase 1,  Beta-ARK-1,  Beta-adrenergic receptor kinase 1,  FLJ16718,  G protein coupled receptor kinase 2,  G-protein coupled receptor kinase 2,  GRK2
Swissprot
Cellular LocalizationCytosol, Plasma Membrane, Other locations: cilium, cytoplasm, membrane.
Concentration0.5 mg/mL
BufferPhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification MethodAffinity purification
Research AreasCancer,  Neuroscience,  Signal Transduction
ConjugationUnconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
ShippingThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
backgroundThe product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Other Clones

1 Results

    Other Formats

    1 Results

    Unconjugated