DVL1 Polyclonal Antibody (E-AB-64060)

For research use only.
Verified Samples |
Verified Samples in IHC: Rat testis, Mouse testis Verified Samples in IF: NIH/3T3 |
Dilution | IHC 1:50-1:200, IF 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC, IF |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human DVL1 (NP_004412.2). |
Abbre | DVL1 |
Synonyms | DRS2, DVL, DVL1, DVL1L1, DVL1P1 |
Swissprot | |
Cellular Localization | Cell membrane. Cytoplasm, cytosol. Cytoplasmic vesicle. Localizes at the cell membrane upon interaction with frizzled family members. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Stem Cells |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. |
Other Clones
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Other Formats
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Unconjugated
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