DTNBP1 Polyclonal Antibody (E-AB-66863)

For research use only.
Verified Samples |
Verified Samples in IHC: Human placenta, Human stomach |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human DTNBP1 (NP_115498.2). |
Abbre | DTNBP1 |
Synonyms | BLOC1S8, DBND, DTNBP1, HPS7, My031, SDY, dysbindin |
Swissprot | |
Cellular Localization | Cytoplasm. Cytoplasmic vesicle membrane. Cytoplasmic vesicle>secretory vesicle>synaptic vesicle membrane. Endosome membrane. Melanosome membrane. Nucleus. Cell junction>synapse>postsynaptic cell membrane>postsynaptic density. Endoplasmic reticulum. Detected in neuron cell bodies, axons and dendrites. Detected at synapses, at post-synaptic density, at pre-synaptic vesicle membranes and microtubules. Detected at tubulovesicular elements in the vicinity of the Golgi apparatus and of melanosomes. Occasionally detected at the membrane of pigmented melanosomes in cultured melanoma cells. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Neuroscience |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene. |
Other Clones
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Other Formats
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Unconjugated
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