CXCL3/CINC-2α/β Polyclonal Antibody(Capture/Detector) (AN003790P)

For research use only.
Verified Samples | Verified Samples in ELISA: Recombinant Human CXCL3/CINC-2α/β protein, Human serum, Human plasma |
Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
Isotype | Rabbit IgG |
Host | Rabbit |
Reactivity | Human |
Applications | ELISA Capture/Detector |
Clonality | Polyclonal |
Immunogen | Recombinant Human CXCL3/CINC-2α/β Protein expressed by E.coli |
Abbre | CXCL3/CINC-2α/β |
Synonyms | GRO, CXCL, SCYB, C-X-C Motif Chemokine, CINC-2b, C-X-C Motif Chemokine 3, GRO-Gamma, GRO-Gamma (1-73), GRO-Gamma (5-73), Growth-Regulated Protein Gamma, Macrophage Inflammatory Protein 2-Beta, MIP2B, MIP-2b, MIP2-Beta, CXCL3, GRO3, GROG, SCYB3 |
Swissprot | |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Purification Method | Antigen Affinity Purification |
Research Areas | Immunology |
Conjugation | Unconjugated |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
background | Human GRO alpha, GRO beta (MIP-2 alpha ), and GRO gamma (MIP-2 beta ) are products of three distinct, non-allelic human genes. GRO beta and GRO gamma share 90% and 86% amino acid sequence homology, respectively, with GRO alpha. All three human GROs are members of the alpha (C-X-C) subfamily of chemokines and are thought to be the homologs of murine KC and MIP-2. The three GRO cDNAs encode 107 amino acid precursor proteins from which the N-terminal 34 amino acid residues are cleaved to generate the mature GROs. There are no potential N-linked glycosylation sites in the amino acid sequences. GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. All three GROs can bind with high affinity to the IL-8 receptor type B. |
Other Clones
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Unconjugated
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