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For research use only.

Verified Samples Verified Samples in WB: HepG2, K562, Jurkat, 231, Hela
Verified Samples in IHC: Human gastric cancer, Human liver cancer
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human MCM5
Abbre CDC46
Synonyms CDC 46,  CDC46,  CDC46 homolog,  Cell division cycle 46,  DNA replication licensing factor,  DNA replication licensing factor MCM 5,  DNA replication licensing factor MCM5,  MCM 5,  MCM5,  MGC5315,  Minichromosome maintenan,  Minichromosome maintenance complex component 5
Swissprot
Calculated MW 82 kDa
Cellular Localization Nucleus.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
Other Clones

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Unconjugated

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