CDC46 Polyclonal Antibody (E-AB-10450)

For research use only.
Verified Samples |
Verified Samples in WB: HepG2, K562, Jurkat, 231, Hela Verified Samples in IHC: Human gastric cancer, Human liver cancer |
Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human MCM5 |
Abbre | CDC46 |
Synonyms | CDC 46, CDC46, CDC46 homolog, Cell division cycle 46, DNA replication licensing factor, DNA replication licensing factor MCM 5, DNA replication licensing factor MCM5, MCM 5, MCM5, MGC5315, Minichromosome maintenan, Minichromosome maintenance complex component 5 |
Swissprot | |
Calculated MW | 82 kDa |
Cellular Localization | Nucleus. |
Concentration | 0.5 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. |
Other Clones
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Other Formats
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Unconjugated
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